Most residents are multilingual so finding someone who speaks English is easy. And with over 180 breweries in this little slice of heaven, it's easy to get caught up in a conversation in one of its many pubs. Be certain that any beer you order will be served in its own unique glass. I've even heard of people changing their beer order if the correct glass isn't available. Now that's what I call a beer lover!
My mother-in-law was also on this trip and we bought tickets for Brussel's hop-on, hop-off bus tour. I highly recommend doing this on your first day in the city as it gives you a great overview of what the city has to offer. There is a also a daily flea market along one of the routes, so you may want to start this tour early in the morning so you can hop off at that stop (unfortunately we didn't have time to get off and check it out - I will definately hit it next time!!)
From there, Bruges is just an hour by car and is considered the Venice of Belgium. There is also a movie titled "In Bruges" which will make you want to see this city for yourself. Take a boat tour on the canal, stop and have some great seafood and explore this walkable city. This is also home to Michelangelo's Madonna with child which is worth visiting. It isn't a huge city so a day or two is all you'll need to see the sights.